Zewail City Researchers Publish a New Study in PLOS One Journal
Through collaboration between the Microbial genomics research group led by Dr. Mohamed Elhadidy, Professor in Zewail City’s Biomedical Sciences Program, and Zewail City’s Center for Genomics, a new study was published in the PLOS ONE journal.
In this study, microbial comparative genomics was performed to identify genomic antimicrobial resistance determinants and genetic relationships between different lineages of Campylobacter (Campoylobacter jejuni and Campoylobacter coli).
Campylobacter is considered to be the most common bacterial cause of human gastroenteritis worldwide. The most common clinical symptoms of Campylobacter-mediated infections include diarrhea, abdominal pain, fever, headache, nausea, and/or vomiting.
Our findings contribute to the identification of transmission dynamics of antimicrobial resistance genes and their distribution by source.
This study reveals the potential of next-generation sequencing technologies for the in silico prediction of novel antimicrobial resistance mechanisms in Campylobacter.
Therefore, this study reflects the importance of implementing next-generation sequencing to set prevention strategies and strict antibiotic stewardship in Egypt, to combat the increasing threat of antimicrobial resistance.